摘要 目的：探究显微镜下经鼻-蝶窦垂体瘤摘除术的临床效果。方法：选取2018年5月至2019年5月广东揭阳市中医院收治的垂体瘤患者104例作为研究对象，按照随机数字表法分为对照组和观察组，每组52例，对照组采用经口唇下鼻中隔蝶窦垂体瘤切除术，观察组采用显微镜下经鼻-蝶窦垂体瘤摘除术，比较2组术后睡眠质量。结果：2组术后生长激素均比术前显著降低，差异有统计学意义(P<0.05)，对照组和观察组组间比较，差异无统计学意义(P>0.05);观察组术后睡眠质量明显优于对照组，差异有统计学意义(P<0.05)。结论：显微镜下经鼻-蝶窦垂体瘤摘除术会引起患者生长激素水平下降，对患者睡眠质量的影响较小。

    关键词 显微镜;经鼻-蝶窦垂体瘤摘除术;垂体瘤;生长激素水平;睡眠质量

    Abstract Objective：To explore the clinical effect of transsphenoidal pituitary resection under microscope.Methods：A total of 104 patients with pituitary adenoma admitted to Jieyang Hospital of Traditional Chinese Medicine from May 2018 to May 2019 were selected as the study subjects.They were divided into control group and observation group according to random number table method ......